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Fig. 1.

FSHR structure and location of the activating mutation. The extracellular domain (EC) consists of several regions, while the transmembrane domain (TM) consists of seven hydrophobic segments spanning the cell membrane. These segments are connected by intra- and extracellular loops. The activating (D540G) mutation is indicated and lies within intracellular domain (IC) 3.

Journal of Animal Reproduction and Biotechnology 2019;34:267~271
© J Anim Reprod Biotechnol