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Fig. 5.

Model showing of hypothesis mechanism of ovine IFNT gene regulation during early pregnancy. A dramatic increase in IFNT gene expression, when CDX2 expression predominates and formation of CREBBP/ETS2/AP1 complex during the pre-attachment period in the ovine uterine (left). Whereas, a dramatic decrease in IFNT gene expression from the decrease of CDX2 expression and association of EOMES with the CREBBP/ETS2/AP1 complex, when conceptus attaches to the uterine epithelium (right).

Journal of Animal Reproduction and Biotechnology 2019;34:292~299
© J Anim Reprod Biotechnol