H&E staining of testis tissue from heat-stress treated male mice. A (control), B (Honey berry), C (Heat shock), D (Honey berry Heat shock), E (Honeyberry Heat shock ×400) (A) Normal testis (B) Normal sperm number is more than control in seminiferous tubule lumen, continuous basement membrane and thick seminiferous tubule (C) Thickness of germinal epithelium is thin, internal bleeding, lack of seminiferous tubule’s sperm, severe necrosis and degeneration of seminiferous tubule (D) Restore of seminiferous tubule’s destruction, production of normal semen in the seminiferous tubule, continuous basement membrane, some of necrosis and degeneration (E) Despite of internal bleeding, production of semen in seminiferous tubule, continuous basement membrane.