PA increases gene expression in inflammatory pathways in human trophoblasts. Changes in mRNA expression levels of NF-κB, IRAK1, IL-1β, IL-6, IL-8, and TNF-α in HTR8/SVneo cells in response to 200 μM PA for 24 h were analyzed by qPCR. Data are presented as representative results from three independent experiments. Asterisks indicate a statistically significant difference compared to controls (***p < 0.001; **p < 0.01; *p < 0.05).