Expression of mRNA levels of anti-inflammatory and anti-tumorigenic molecules in 2D-monolayer and 3D-spheroid RA-hMSCs with SF treatments. Two different RA patients derived MSCs from synovial fluid, RA-hMSCs-1 (A) and -2 (B). The anti-inflammatory related genes (TSG-6, STC1 and LIF), anti-tumorigenic related genes (IL-24 and TRAIL), MSC homing receptors (CXCR4), and Wnt signaling inhibitor (DKK1) were evaluated in SF treated and non-treated 2D-monolayer cultured RA-hMSCs, SF treated 3D-shperiod RA-hMSCs by qRT-PCR analysis. All data was normalized against YWHAZ Values are mean ± SD (**p < 0.01, ***p < 0.001).
pISSN: 2671-4639
