Stem cell therapy for inner/outer retinal diseases. (A) Injection of iPSC-derived retinal cells to target integration in GCL or ONL. (B) Reporter (green) expression in GC and rod photoreceptors in GCL and ONL respectively are due to cytoplasmic material transfer rather than integration. GC, ganglion cell; GCL, ganglion cell layer; INL, inner nuclear layer; iPSC, induced pluripotent stem cell; MG, muller glia; NFL, nerve fiber layer; ONL, outer nuclear layer; RPE, retinal pigment epithelium.
pISSN: 2671-4639
