Catechin hydrate ameliorated cisplatin-induced GC-1 spg apoptosis. (A) Dot plots were used to visualize flow cytometric analysis of apoptosis in the samples treated with combined cisplatin and catechin hydrate. (B) Apoptotic index data summarizing the results, presented as the mean ± SEM from three independent experiments (n = 4). Significant differences compared to the control are indicated by *p < 0.05; **p < 0.01. (C) The protein levels of apoptotic-related factors such as cleaved caspase 3 and BAX. (D) The graph presents the protein level relative to the β-actin level or the level of the inactive form. The data shown as the mean ± SEM with four determinations per condition. **p < 0.01.