Antioxidant and anti-inflammatory mechanisms of catechin hydrate in cisplatin-induced GC-1 spg cell damage. (A) Nrf2 mRNA expression in cisplatin and catechin-hydrate-treated GC-spg after cultured 24 h. The graph shows the mean ± SEM in the log 2 scale. (B) CellROX staining in cisplatin- and catechin-hydrate-treated GC-1 sgp cells. CellROX staining intensity was analyzed using Image J software. Data are shown as a graph with the mean ± SEM. *p < 0.05; **p < 0.01. Scale bar = 100 μm. (C) mRNA expression levels of iNOS and COX2 in each sample. The graph shows the mean ± SEM of the mean in the log 2 scale. (D) The protein expression levels of COX2, iNOS, and β-actin in each sample. The graph shows the relative protein levels as the mean ± SEM. COX2 and iNOS expression levels were normalized to β-actin levels. **p < 0.01.
pISSN: 2671-4639
